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Updated: Aug 21, 2026

Characterization of Thymus-dependent and Thymus-independent Immunoglobulin Isotype Responses in Mice Using Enzyme-linked Immunosorbent Assay
Published on: September 7, 2018
Antigens and immunity in Theileria annulata
1Wellcome Unit of Molecular Parasitology, University of Glasgow, Bearsden Road, Glasgow G6 I I QH, UK.
Abstract:
About 200 million cattle are believed to be at risk from the debilitating and often fatal effects of tropical theileriosis, caused by Theileria annulata. Currently, there is no very cheap effective drug for treatment of T. annulata infections, although the hydroxynophthoquinones parvaquone and buparvaquone are reported to give good results(1-4). Control of the parasite principally involves vector control against the ixodid tick vectors - mainly by cattle dipping and spraying with acaricides - and vaccination using attenuated macroschizont-infected leucocytes (1-17) (see Box I). In this article, Roger Hall discusses the nature of immunity that can be achieved against T. annulata, and progress in identifying the main antigens involved in this immunity.
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