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Updated: Aug 17, 2026

Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation
Published on: June 5, 2012
Protective immunity and vaccines to schistosomiasis
1Department of Microbiology and Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Abstract:
Human schistosomiasis is a major health problem in endemic areas and it is estimated that world-wide more than 200 million people are infected. Active infection, exposure to attenuated parasites, or appropriate immunization with parasite extracts or purified antigens can lead to partial protection against challenge infections. Studies of the humoral and cellular mechanisms responsible for these forms of resistance, and the definition, purification or production of recombinant moieties responsible for the induction of immunity are currently the focus of considerable research efforts.
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