Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Iron and malaria.

S J Oppenheimer¹

¹Department of Paediatrics, University Sains Malaysia, 15990 Kato Bhoru, Kelantan, Malaysia.

Parasitology Today (Personal Ed.)

|March 1, 1989

Summary

This summary is machine-generated.

Iron supplementation programs in developing nations may increase malaria risk. Caution is advised, especially for infants and pregnant women, due to potential adverse health outcomes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Ultrastructural assessment of Plasmodium falciparum in age-fractionated thalassaemic erythrocytes.

Parasitology research·2005

Same author

Polynesian origins. Slow boat to Melanesia?

Nature·2001

Same author

Iron and its relation to immunity and infectious disease.

The Journal of nutrition·2001

Same author

Iron and infection in the tropics: paediatric clinical correlates.

Annals of tropical paediatrics·1999

Same author

Red cell age and susceptibility to malaria during pregnancy.

Acta obstetricia et gynecologica Scandinavica·1998

Same author

Thalassaemia trait, red blood cell age and oxidant stress: effects on Plasmodium falciparum growth and sensitivity to artemisinin.

Transactions of the Royal Society of Tropical Medicine and Hygiene·1998

Same journal

Immune effector mechanisms in parasitic infections.

Parasitology today (Personal ed.)·2006

Same journal

Nitric oxide in health and disease.

Parasitology today (Personal ed.)·2006

Same journal

Infection, oxford general practice series 40.

Parasitology today (Personal ed.)·2006

Same journal

Parasitism and the platyhelminthes.

Parasitology today (Personal ed.)·2006

Same journal

Reply.

Parasitology today (Personal ed.)·2006

Same journal

Waterborne cryptosporidiosis and the need for legislation.

Parasitology today (Personal ed.)·2006

See all related articles

Area of Science:

Global Health
Infectious Diseases
Nutritional Science

Background:

Iron deficiency is a widespread health issue in developing regions.
Mass iron supplementation and presumptive therapy are common public health interventions.
Malaria is a significant endemic disease in many of these areas.

Purpose of the Study:

To evaluate the potential risks of iron supplementation programs in malaria-endemic regions.
To highlight emerging evidence suggesting a link between iron therapy and increased malaria incidence.
To emphasize the need for caution in implementing widespread iron supplementation strategies.

Main Methods:

Review of recent scientific evidence and epidemiological data.
Analysis of the physiological interactions between iron status and malaria parasite.

Related Experiment Videos

Consideration of vulnerable populations, including infants and pregnant women.

Main Results:

Emerging evidence indicates that iron supplementation may elevate the risk of developing patent malaria.
This association appears particularly pronounced in individuals with developing or compromised immunity.
Infants and pregnant women are identified as high-risk groups due to lower immunity and potential fetal complications.

Conclusions:

Presumptive iron therapy and mass supplementation require careful consideration in malaria-endemic zones.
The potential for increased malaria incidence necessitates a re-evaluation of current supplementation guidelines.
Further research is crucial to understand and mitigate the risks associated with iron interventions in vulnerable populations.