Related Experiment Video
Updated: Aug 21, 2026

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
Published on: January 27, 2019
Comparison of genes encoding Trypanosoma cruzi antigens
A C Frasch1, J J Cazzulo, L Aslund
1Instituto de Investigociones Bioquimicos, Fundocion Campomar, Antonio Machado 151, 1405 Buenos Aires, Argentina.
Abstract:
Trypanosoma cruzi, the causative agent of Chagas disease, simultaneously expresses several different surface antigens. This contrasts sharply with blood-stream forms o f the African trypanosomes, which display only one variant surface glycoprotein at a time. Over the past few years, the genes coding for a number of T. cruzi proteins recognized by sera from patients have been cloned and at least partially sequenced. However, some of those discovered in more than one laboratory have been given different names. Here, Carlos Frasch, Juan Cazzulo, Lena Aslund and UIf Pettersson try to systematize the literature available on these antigens, including what is known about their localization and function.
More Related Videos
Related Concept Videos
American Trypanosomiasis
Diversity of Antigen Receptors
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
Exon Recombination
Exon shuffling follows “splice frame rules.” Each exon has three reading...
Antigen Processing Pathways
MHC Class I: Presenting Endogenous...

