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Avermectins in arthropod vector management - prospects and pitfalls.
1Yale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06510, USA.
Parasitology Today (Personal Ed.)
|March 1, 1993
Summary
Avermectins show promise in controlling disease vectors by reducing their survival and reproduction. However, careful integration into existing control programs is crucial to mitigate risks like non-target effects and resistance.
Area of Science:
- Vector-borne disease control
- Medical entomology
- Parasitology
Background:
- Avermectins are a class of compounds with demonstrated efficacy against various arthropod vectors.
- Vector-borne diseases pose a significant global health challenge, necessitating novel control strategies.
Purpose of the Study:
- To evaluate the potential of avermectins in reducing vector populations and mitigating vector-borne disease.
- To discuss the integration of avermectins into existing vector management schemes.
Main Methods:
- Review of experimental data on avermectin impact on vector survival, abundance, and development.
- Analysis of sublethal effects, including fecundity and parasite uptake.
- Consideration of ecological impacts and resistance development.
Main Results:
- Avermectins significantly decrease survival and abundance in various vector species.
- Sublethal effects observed include prolonged development, reduced fecundity, and diminished parasite uptake.
- Potential risks include impacts on non-target species and the evolution of resistance.
Conclusions:
- Avermectins offer a promising new tool for vector control, potentially reducing vector-borne disease incidence.
- Cautious optimism is warranted, emphasizing the need for integrated management strategies.
- The ultimate value must be assessed by reduced parasite transmission, not solely vector abundance.