Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Secretory transport in Plasmodium.

H G Elmendorf1, K Haldar

  • 1Department of Microbiology and Immunology, Standford University School of Medicine, Stanford, CA 94305, USA.

Parasitology Today (Personal Ed.)
|March 1, 1993
PubMed
Summary

The malaria parasite Plasmodium falciparum remodels red blood cells for nutrient uptake. This review proposes a model for protein secretion and trafficking in Plasmodium falciparum during its asexual blood stage.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Laparoscopic pelvic side-wall resection: video vignette of the surgical anatomy.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2016
Same author

Constitutive modelling of magnetic shape memory alloys with discrete and continuous symmetries.

Proceedings. Mathematical, physical, and engineering sciences·2014
Same author

Should pelvic exenteration for symptomatic relief in gynaecology malignancies be offered?

Archives of gynecology and obstetrics·2013
Same author

Serous endometrial intraepithelial carcinoma: a case series and literature review.

Cancer management and research·2013
Same author

Utility of peritoneal lavage cytology during laparoscopic salpingo-oophorectomy: a retrospective analysis.

BJOG : an international journal of obstetrics and gynaecology·2010
Same author

Aggressive angiomyxoma: a case series and literature review.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2009

Area of Science:

  • Malariology
  • Cell Biology
  • Parasitology

Background:

  • The asexual blood stage of Plasmodium falciparum occurs within mature erythrocytes, which lack organelles and have limited biosynthetic capacity.
  • Despite the host cell's limitations, the parasite actively grows, divides, and requires nutrient uptake and waste expulsion.
  • Plasmodium falciparum extensively modifies the erythrocyte to support its survival and metabolic needs.

Purpose of the Study:

  • To propose a model for protein secretion and trafficking in Plasmodium falciparum.
  • To explain how the parasite remodels the host erythrocyte for survival and nutrient acquisition.

Main Methods:

  • This is a review article, therefore no experimental methods were employed.
  • The authors synthesize existing research on Plasmodium falciparum secretion and trafficking.

Main Results:

  • The parasite exports numerous proteins to modify the erythrocyte.
  • The parasite establishes machinery for protein trafficking within the remodeled erythrocyte.

Conclusions:

  • A model for secretion in Plasmodium falciparum is proposed.
  • Understanding parasite-host cell interactions is crucial for malaria parasite survival.

Related Experiment Videos