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Immunometabolic Circuits in Infection for Advancing Host Directed Therapies
Published on: September 13, 2024
Intermediary metabolism of Leishmania
1Duke University Medical Center, Department of Cell Biology, Division of Physiology, PO Box 3709, Durham, NC 27710, USA.
Abstract:
In the course of their existence, parasites develop several metabolic pathways that differ significantly from those of their hosts. Despite the fairly close evolutionary kinship between Leishmania donovani and Trypanosoma brucei, the forms that live in the insect vectors have evolved different strategies for the disposition of available food resources. In this brief review, Joseph Blum will focus on the data available from studies on Leishmania spp and will largely ignore the information available from Trypanosoma spp.
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