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Updated: Aug 21, 2026
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Standardized Measurement of Nasal Membrane Transepithelial Potential Difference (NPD)
Published on: September 13, 2018
Measurement of chloride transport in nasal epithelial cells by X-ray microanalysis
Anca Dragomir1, Charlotte Andersson, Godfried M Roomans
1Department of Medical Cell Biology, University of Uppsala, Box 571, 75123 Uppsala, Sweden.
Abstract:
Nasal epithelial cells are a representative and easy to obtain system of epithelial cells for the study of chloride transport. X-ray microanalysis (XRMA) allows the direct and simultaneous measurement of several elements of biological interest, including chloride. Here, a method is presented for the preparation of nasal epithelial cells for X-ray microanalysis and for the determination of chloride transport by this analytical technique.
