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Published on: October 3, 2014
Cardiac tissue engineering: regeneration of the wounded heart
Prisca Zammaretti1, Marisa Jaconi
1Institute for Biomedical Engineering, Swiss Federal Institute, Moussonstrasse, 18, 8044 Zurich.
Abstract:
New solutions are needed to regenerate hearts damaged by myocardial infarction, to overcome bad prognosis of patients with heart failure, and to address the shortage of heart donors. In the past few years, cardiac tissue engineering has emerged as a new and ambitious approach that combines knowledge from material chemistry with cell biology and medicine. In this short review, we present an overview on the most promising materials and cell-therapy strategies used in the past few years for the regeneration of the wounded heart.
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