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Published on: July 6, 2015
Involution of threshold retinopathy of prematurity after diode laser photocoagulation
David K Coats1, Aaron M Miller, Kathryn M Brady McCreery
1Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas 77030, USA. dcoats@bcm.tmc.edu
Objective:
To characterize the process of involution of threshold retinopathy of prematurity after transpupillary diode laser photocoagulation.
Design:
Retrospective case series.
Participants:
Neonates with threshold retinopathy who underwent diode laser photocoagulation of the peripheral avascular retina.
Methods:
A retrospective chart review was done of the weekly examination records of infants treated for threshold disease. Features that were studied included the presence of residual stage 3 neovascularization, plus disease, and development of retinal detachment (RD).
Main Outcome Measures:
Timing of full involution and/or development of an RD.
Results:
Of 262 eyes of 138 infants treated, full involution without RD was seen in 8%, 43%, 64%, 73%, and 86% of eyes at postoperative weeks 1, 2, 3, 4, and 9+/-3, respectively. Retinal detachments were diagnosed cumulatively in 0%, 1.5%, 4.2%, 6.5%, and 14% of eyes at weeks 1, 2, 3, 4, and 9+/-3, respectively.
Conclusions:
Full involution of laser-treated threshold retinopathy of prematurity required more than 2 weeks in more than half of treated eyes. Most RDs were not detected until > or =3 weeks after treatment.
