Related Experiment Video
Updated: Aug 21, 2026
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Conjunctival metastasis as initial sign of disseminated cutaneous melanoma
Jerry A Shields1, Carol L Shields, Ralph C Eagle
1Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Purpose:
To describe a patient with conjunctival metastasis as the initial manifestation of metastasis from a cutaneous melanoma.
Design:
Single interventional case report.
Methods:
A 48-year-old woman with a history of cutaneous axillary melanoma developed a rapidly growing conjunctival mass. Subsequent systemic evaluation disclosed asymptomatic liver metastasis. The conjunctival lesion was resected.
Results:
Histopathologic evaluation of the conjunctival tumor disclosed an epithelioid cell melanoma located in the conjunctival stroma, without appreciable junctional activity, compatible with metastatic melanoma.
Conclusions:
Conjunctival metastasis from cutaneous melanoma can rarely be the initial manifestation of disseminated melanoma.
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