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Multiple hibernomas in a 1-month-old female infant
Erol Baskurt1, Diana M Padgett, Julie A Matsumoto
1Department of Radiology, University of Virginia, Charlottesville, VA, USA.
AJNR. American Journal of Neuroradiology
|October 7, 2004
Summary
Hibernoma, a rare benign tumor of fetal brown fat, is infrequently documented. This report details a unique case of multiple hibernomas in a one-month-old infant, expanding the known age range for this condition.
Area of Science:
- Histopathology
- Pediatric Oncology
- Soft Tissue Tumors
Background:
- Hibernoma is a rare, benign soft tissue neoplasm originating from brown adipose tissue remnants.
- Literature reports typically describe hibernomas in adults, with limited pediatric cases.
- The tumor's etiology and typical presentation are well-established but rarely observed in neonates.
Observation:
- A one-month-old infant presented with multiple soft tissue masses.
- Initial clinical presentation did not immediately suggest hibernoma.
- Diagnostic imaging and subsequent histopathological examination confirmed the presence of multiple hibernomas.
Findings:
- Histopathological analysis confirmed the diagnosis of hibernoma, characterized by mature brown fat cells.
- The presence of multiple hibernomas in a neonate is exceptionally rare.
- This case expands the known clinical spectrum and age distribution of hibernoma.
Implications:
- Highlights the importance of considering hibernoma in the differential diagnosis of soft tissue tumors in infants.
- Suggests potential for earlier presentation or underdiagnosis in the pediatric population.
- Contributes to a broader understanding of the rare pediatric soft tissue tumor landscape.