Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Nephron sparing surgery].

S Salciccia1, R Cirocchi, P Salciccia

  • 1Unità Operativa di Urologia, ASL 2, Urbino, Italy.

Minerva Urologica E Nefrologica = the Italian Journal of Urology and Nephrology
|October 7, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A SICE (Società Italiana di Chirurgia Endoscopica e Nuove Tecnologie) observational prospective multicenter study on lymphadenectomy during right hemicolectomy: Should anatomical variability of the right colic artery influence the surgical strategy?-CoDIG 2 database (ColonDx Italian Group).

Updates in surgery·2025
Same author

A SICE (Società Italiana di Chirurgia Endoscopica e Nuove Tecnologie) observational prospective multicenter study on anatomical variants of the superior mesenteric artery: intraoperative analysis during laparoscopic right hemicolectomy-CoDIG 2 database (ColonDx Italian Group).

Updates in surgery·2024
Same author

Laparoscopic right hemicolectomy: a SICE (Società Italiana di Chirurgia Endoscopica e Nuove tecnologie) network prospective study on the approach to right colon lymphadenectomy in Italy: is there a standard?-CoDIG 2 (ColonDx Italian Group).

Surgical endoscopy·2024
Same author

COVID-19 and kidney: role of SARS-CoV-2 infection in the induction of renal damage.

European review for medical and pharmacological sciences·2023
Same author

Serial transverse enteroplasty (STEP) in case of short bowel syndrome: did we achieve our goal? A systematic review.

Updates in surgery·2022
Same author

The impact of transanal local excision of early rectal cancer on completion rectal resection without neoadjuvant chemoradiotherapy: a systematic review.

Techniques in coloproctology·2021
Same journal

Trimodal therapy in muscle invasive bladder cancer management.

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2020
Same journal

Is androgen deprivation therapy protective against SARS-CoV-2 infection and related complications in prostate cancer patients?

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2020
Same journal

Bowel suture technique for bladder neck reconstruction during RALP and its impact on early continence recovery.

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2020
Same journal

Systematic review of neoadjuvant therapy by immune checkpoint inhibitors before radical cystectomy: where do we stand?

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2020
Same journal

Functional and oncological outcomes of 3D clampless sutureless laparoscopic partial nephrectomy for renal tumors with low nephrometry score.

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2020
Same journal

Robot-assisted laparoscopic pyeloplasty in children: a systematic review.

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2020
See all related articles

Nephron sparing surgery (NSS) is a safe and effective treatment for small renal masses, showing no severe renal function impairment or recurrence in early follow-up. This kidney-preserving approach offers a viable alternative to radical nephrectomy.

Area of Science:

  • Urology
  • Nephrology
  • Oncology

Context:

  • Partial nephrectomy (PN) is established for patients with compromised renal function or solitary kidneys.
  • The efficacy of PN for small renal masses in patients with a normal contralateral kidney remains a subject of ongoing discussion.
  • This study compares NSS with radical nephrectomy (RN) in a matched cohort.

Purpose:

  • To evaluate the effectiveness and safety of nephron sparing surgery (NSS) versus radical nephrectomy (RN) for localized, small renal masses (<4 cm).
  • To compare outcomes including renal function, complications, and survival rates between NSS and RN.

Summary:

  • A retrospective analysis of 12 patients undergoing NSS and 12 matched patients undergoing RN for small renal masses (<4 cm).
  • All NSS procedures were completed successfully with no major bleeding or urine leakage.

Related Experiment Videos

  • No severe renal function impairment was observed post-operatively, and overall survival was 100% with no recurrences at a mean follow-up of 24 months.

    • Impact:

    • Partial nephrectomy demonstrates a safe profile with low morbidity for small peripheral renal lesions.
    • Early follow-up suggests no definitive recurrences, though long-term cancer-specific survival assessment requires extended observation (over 10 years).
    • NSS offers a promising kidney-preserving option for select patients with renal cell carcinoma.