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[Migraine and psychiatric disorders].

Ole Bernt Fasmer1, Ketil Joachim Oedegaard

  • 1Psykiatrisk institutt, Universitetet i Bergen, Haukeland Universitetssykehus, 5021 Bergen. ole.fasmer@psyk.uib.no

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|October 7, 2004
PubMed
Summary

Migraine, mood, and anxiety disorders share clinical features and potential causes. Treatments like tricyclic antidepressants and valproate may benefit patients with these interconnected conditions.

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Area of Science:

  • Neurology
  • Psychiatry
  • Clinical Medicine

Context:

  • Migraine, mood disorders, and anxiety disorders affect 10-20% of the population.
  • These conditions share clinical similarities and potential pathogenetic mechanisms.
  • Strong comorbidity exists between migraine and psychiatric disorders, particularly bipolar II disorder.

Purpose:

  • To review the literature on the connections between migraine and psychiatric disorders.
  • To highlight shared clinical features and potential pathophysiological mechanisms.
  • To inform clinicians about these associations.

Summary:

  • Migraine attacks can include psychiatric symptoms, and mood/anxiety disorders often present episodically, similar to migraine.
  • Epidemiological data reveal a high prevalence of depression and anxiety disorders in migraine patients.

Related Experiment Videos

  • Dysregulation of monoaminergic systems, especially serotonin, is implicated in the pathophysiology of these disorders.
  • Tricyclic antidepressants and valproate show efficacy in treating migraine, mood, and anxiety disorders.
  • Impact:

    • Increased awareness of the link between migraine and psychiatric conditions for healthcare providers.
    • Potential for integrated treatment approaches targeting shared mechanisms.
    • Improved patient management through recognition of comorbidity.