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Updated: Aug 21, 2026
Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease
Published on: August 30, 2011
[Event-related potentials and the diagnosis of short-term verbal memory disorders in cerebrovascular disease]
E Alonso-Prieto1, E Palmero-Soler, C Trujillo-Matienzo
1Departamento de Neuropsicología, Instituto de Neurología y Neurocirugía, Ciudad Habana, Cuba.
Introduction:
Cerebrovascular disease can cause different memory disorders depending on the area of the brain involved. More specifically, ischemic lesions in the frontal region can be associated to short-term verbal memory disorders.
Patients And Methods:
Two groups of subjects were studied, 10 of whom were patients who presented a frontal cerebral infarction and 10 healthy controls. They were administered a memory task involving word recognition. While they were performing the task the electrical activity of their brains was recorded in order to examine event-related potentials (ERP).
Results:
The patients' performance of the task was poorer than that of the healthy control subjects. Likewise, while the latter displayed a predominantly frontal distribution of ERPs, in the patients the frontal activity diminished and was seen to be chiefly temporoparietooccipital.
Conclusions:
These findings allow important conclusions to be drawn about the characteristics of the memory disorder presented by these patients.
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