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Updated: Aug 21, 2026

Structure-Guided Design and Development of Novel Cyclophilin A Inhibitors and Ganoderiol-F Derivatives: An In-Silico Approach
Published on: June 23, 2026
MSDsite: a database search and retrieval system for the analysis and viewing of bound ligands and active sites
Adel Golovin1, Dimitris Dimitropoulos, Tom Oldfield
1EMBL Outstation, The European Bioinformatics Institute, Welcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
Abstract:
The three-dimensional environments of ligand binding sites have been derived from the parsing and loading of the PDB entries into a relational database. For each bound molecule the biological assembly of the quaternary structure has been used to determine all contact residues and a fast interactive search and retrieval system has been developed. Prosite pattern and short sequence search options are available together with a novel graphical query generator for inter-residue contacts. The database and its query interface are accessible from the Internet through a web server located at: http://www.ebi.ac.uk/msd-srv/msdsite.
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