Related Experiment Video
Updated: Aug 21, 2026

Construction of Model Lipid Membranes Incorporating G-protein Coupled Receptors (GPCRs)
Published on: February 5, 2022
Modulation of AraC family member activity by protein ligands
1Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, FL 33136, USA. gplano@med.miami.edu
Abstract:
A number of AraC family transcriptional activators bind low-molecular-weight ligands that modulate the activity of these proteins. Recently, it has become clear that the activity of several virulence-related AraC family members is regulated through the direct interaction of protein ligands. These interactions, in general, function to activate or repress the transcription of virulence genes in response to specific extracellular stimuli. The identification and characterization of several protein ligands that modify the activity of AraC family members in Pseudomonas aeruginosa and Salmonella enterica are discussed herein.
More Related Videos
10:01Structure-Guided Design and Development of Novel Cyclophilin A Inhibitors and Ganoderiol-F Derivatives: An In-Silico Approach
Published on: June 23, 2026
07:13Characterizing Modulators of Protease-Activated Receptors with a Calcium Mobilization Assay Using a Plate Reader
Published on: May 24, 2024
Related Concept Videos
IP3/DAG Signaling Pathway
GPCRs Regulate Adenylyl Cylase Activity
Two...
Calmodulin-dependent Signaling
The Ca2+-CaM complex does not have enzymatic activity by itself. Instead, the complex binds downstream target proteins, including membrane proteins or enzymes,...
Activation and Inactivation of G Proteins
Amplifying Signals via Enzymatic Cascade
Amplifying Signals via Second Messengers