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Caveolae meet endosomes: a stable relationship?
1Institute for Molecular Bioscience and Centre for Microscopy and Microanalysis, University of Queensland, Queensland 4072, Australia.
Developmental Cell
|October 8, 2004
Abstract:
The endocytic trafficking of caveolae has been the subject of some controversy for many years. A new study (Pelkmans et al.) shows that budded caveolae can interact with both the caveosome and the early endosome and that caveolin-enriched regions of the early endosomal membrane form unusually stable domains that can incorporate cargo in a regulated manner.