Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[The diabetic hand].

F Schiavon, C Circhetta, L Dani

    Reumatismo
    |October 8, 2004
    PubMed
    Summary
    This summary is machine-generated.

    Diabetes mellitus (DM) can cause debilitating hand conditions like Dupuytren's contracture. Good glycaemic control through lifestyle and medication can prevent or improve these rheumatic issues.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Clinical and histopathological features of a population-based cohort of 95 consecutive patients with immunoglobulin G4-related disease in Stockholm, Sweden, during a five-year period.

    Scandinavian journal of rheumatology·2026
    Same author

    SARS-CoV-2 infection in patients with autoimmune rheumatic diseases in northeast Italy: A cross-sectional study on 916 patients.

    Journal of autoimmunity·2020
    Same author

    Wegener's granulomatosis confined to nervous system.

    BMJ case reports·2011
    Same author

    [Septic arthritis: a 12 years retrospective study in a rheumatological university clinic].

    Reumatismo·2009
    Same author

    PEG-modified glucose oxidase immobilized on a PVA cryogel membrane for amperometric biosensor applications.

    Talanta·2008
    Same author

    Rheumatoid arthritis is the major risk factor for septic arthritis in rheumatological settings.

    Autoimmunity reviews·2008
    Same journal

    Delayed referral, socioeconomic status, and disease characteristics as factors associated with disabilities in rheumatoid arthritis patients: a multicenter observational study.

    Reumatismo·2026
    Same journal

    Telerheumatology to improve first access outcomes in outpatients: a prospective monocentric pilot study.

    Reumatismo·2026
    Same journal

    Hypocomplementemic urticarial vasculitis: a rare presentation revealing systemic lupus erythematosus and Sjögren's disease.

    Reumatismo·2026
    Same journal

    Is there still someone laughing at Christopher Columbus?

    Reumatismo·2026
    Same journal

    Concurrent herpetic hypertensive anterior uveitis and cytomegalovirus retinitis in a non-HIV patient with melanoma differentiation-associated gene-5 dermatomyositis: intravenous immunoglobulin comes to the rescue.

    Reumatismo·2026
    Same journal

    Myasthenic syndrome in systemic lupus erythematosus successfully treated with plasma exchange: through one of the unexplored faces of neuropsychiatric involvement.

    Reumatismo·2026
    See all related articles

    Area of Science:

    • Endocrinology
    • Rheumatology
    • Metabolic Disorders

    Background:

    • Diabetes mellitus (DM) is a chronic metabolic disease defined by hyperglycemia, leading to severe microvascular and macrovascular complications.
    • DM is linked to a higher prevalence of hand musculoskeletal disorders, including palmar flexor tenosynovitis, Dupuytren's contracture, limited joint mobility, carpal tunnel syndrome, Charcot arthropathy, and reflex sympathetic dystrophy.
    • These hand abnormalities are more common in individuals with type 1 and type 2 diabetes, correlating with disease duration rather than age or sex.

    Discussion:

    • The pathogenesis of diabetes-associated hand conditions is multifactorial, involving advanced glycation end products, oxidative stress, and altered extracellular matrix metabolism.
    • Early recognition and management of these conditions are crucial to mitigate patient morbidity and improve quality of life.

    Related Experiment Videos

  • Understanding the specific mechanisms underlying each hand disorder in diabetic patients can guide targeted therapeutic strategies.

    • Key Insights:

    • Maintaining optimal glycemic control is paramount in preventing or ameliorating diabetes-related hand conditions.
    • A comprehensive management approach integrating exercise, diet, and pharmacological interventions is essential.
    • Specific hand conditions like Dupuytren's contracture and carpal tunnel syndrome require tailored treatment plans within the context of overall diabetes management.

    Outlook:

    • Further research into the precise molecular pathways linking hyperglycemia to specific hand pathologies may reveal novel therapeutic targets.
    • Developing standardized screening protocols for hand abnormalities in diabetic populations could facilitate earlier diagnosis and intervention.
    • Longitudinal studies are needed to evaluate the long-term efficacy of various management strategies for diabetes-associated hand conditions.