Related Experiment Videos
Midazolam sedation reversed with flumazenil for cardioversion
M E Fennelly1, H Powell, D C Galletly
1Department of Anaesthetics, Royal Postgraduate Medical School, Hammersmith Hospital, London.
British Journal of Anaesthesia
|March 1, 1992
Abstract:
Midazolam was used for anaesthesia in 20 patients undergoing cardioversion; 10 received flumazenil, which caused immediate rapid reversal of anaesthesia, and these patients maintained SpO2 greater than 95%, breathing air, within 5-10 min. In contrast, patients in the placebo group were still partially sedated and required oxygen therapy for up to 2 h to maintain a normal SpO2. Arterial pressure, but not heart rate, also was greater in the flumazenil group in the recovery period.