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[Endovascular treatment of vertebral artery origin stenosis in high risk patients]
Osman Kizilkiliç1, Levent Oğuzkurt, Tülin Yildirim
1Başkent Universitesi Adana Uygulama ve Araştirma Hastanesi, Radyoloji Kliniği, Adana, Turkey.
Insights
Vertebral artery origin stenting is a safe and effective treatment for high-risk patients with atherosclerotic stenosis, preventing stroke and restenosis.
Area of Science:
- Neurology
- Vascular Surgery
- Interventional Cardiology
Background:
- Atherosclerotic stenosis at the vertebral artery origin is a common cause of vertebrobasilar stroke.
- High-risk patients with concomitant conditions often have poor outcomes with medical therapy alone.
Purpose of the Study:
- To evaluate the safety and efficacy of primary stenting for vertebral artery origin stenosis in high-risk patients.
Main Methods:
- 14 high-risk patients (58-74 years) with significant vertebral artery origin stenosis underwent primary stenting.
- Stenoses were detected before coronary artery surgery or after posterior circulation stroke/vertebrobasilar insufficiency evaluation.
- Successful stent placement was achieved in all patients.
Main Results:
- All stenoses were successfully treated with stent placement.
- One patient experienced a left posterior cerebral artery infarction; all others had uneventful procedures.
- Follow-up (3-12 months) showed no stent restenosis or new neurologic deficits.
Conclusions:
- Vertebral artery origin stenosis is a significant cause of vertebrobasilar stroke.
- Primary stenting combined with medical treatment is a safe and effective option for high-risk patients.
- This approach reduces the risk of stroke and restenosis.
Purpose:
Atherosclerotic stenosis of the vertebrobasilar system most commonly occurs at the vertebral artery origin. Stenting of these stenotic lesions in combination with antithrombotics with or without anticoagulants is a safe and effective treatment method. The purpose of this study is to present the results of vertebral artery origin stenting in 14 high-risk patients.
Materials And Methods:
Significant vertebral artery origin stenosis was treated with primary stenting in 14 patients, aged between 58 and 74 years (mean, 66+/-5.3 years). Eleven patients were male, and three were female. Vertebral artery stenosis was detected in eight patients prior to coronary artery surgery, and in six patients after a posterior system stroke or during evaluation of a vertebrobasilar insufficiency. All stenosis were successfully treated with stent placement. Except one patient who had a left posterior cerebral artery infarction, all patients had an uneventful procedure without any complication. Third-month and sixth-month clinical and color Doppler follow-up examinations were available in ten patients, and 12th-month control angiography performed in three patients did not show stent restenosis. None of the patients had new neurologic deficit during the follow-up.
Conclusion:
Vertebral artery origin stenoses are one of the most common causes of vertebrobasilar stroke. In the presence of concomitant cerebral artery stenosis or systemic disorders, patients are under high risk even if they are on medical therapy. Primary stenting combined with medical treatment is a safe and effective treatment modality.
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