Apoptosis in human ejaculated spermatozoa

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Flow Cytometric Analysis of Biomarkers for Detecting Human Sperm Functional Defects
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Flow Cytometric Analysis of Biomarkers for Detecting Human Sperm Functional Defects

Published on: April 21, 2022

G J E Oosterhuis1, I Vermes

  • 1Medisch Spectrum Twente Hospital Group, Enschede, The Netherlands. j.oosterhuis@ziekenhuis-mst.nl

Journal of Biological Regulators and Homeostatic Agents
|October 9, 2004
PubMed

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Apoptosis

Apoptosis is a combination of two Greek words, 'apo' and 'ptosis,' meaning separation and falling off, respectively. Hippocrates used this word to describe gangrene, which was caused due to bandaging of fractured bones. Apoptosis was distinguished from necrosis in 1970 when John Kerr reported observations of morphological changes occurring during apoptosis. During one experiment, he observed that the disruption of blood supply to the liver tissue resulted in a size reduction of the tissue.
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