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Kluver-Bucy syndrome -- an experience with six cases
1Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, India. sjha@sgpgi.ac.in.
Neurology India
|October 9, 2004
Summary
Kluver-Bucy syndrome (KBS) is a rare neurobehavioral disorder. This study found KBS in children with various neurological conditions, often presenting with seizures and behavioral changes, indicating a poor prognosis.
Area of Science:
- Neurology
- Neuroscience
- Pediatrics
Background:
- Kluver-Bucy syndrome (KBS) is a complex neurobehavioral disorder.
- It is associated with diverse underlying neurological conditions.
- Understanding KBS manifestations and associations is crucial for diagnosis and management.
Observation:
- A review of 6 pediatric cases of KBS (ages 4-14) over 5 years was conducted.
- Common symptoms included hyperorality, hypersexuality, and altered behaviors.
- Five out of six patients experienced recurrent unprovoked seizures.
Findings:
- The etiological spectrum of KBS in this cohort included anoxia-ischemic encephalopathy, herpes simplex encephalitis, neurocysticercosis (NCC), traumatic brain injury, and tuberculous meningitis.
- Prognosis was generally poor, with the exception of the patient diagnosed with NCC.
Implications:
- This case series highlights the varied neurological origins of KBS in children.
- Early identification and etiological diagnosis are vital for appropriate patient care.
- The findings suggest NCC may have a better prognosis compared to other KBS-associated neurological disorders in pediatric populations.