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Large-scale carbohydrate analysis by capillary array electrophoresis: part 1. Separation and scale-up
Julia Khandurina1, Nels A Olson, Abraham A Anderson
1Diversa Corporation, San Diego, CA 92121, USA. jkhandurina@diversa.com
Electrophoresis
|October 9, 2004
Abstract:
A 96-capillary array electrophoresis (CAE) instrument has been adapted for large-scale mono- and oligosaccharide analysis and characterization. Operational protocols and data processing tools have been developed to optimize the CAE system for this application. Effects of different additives to the running buffer on efficiency and capillary-to-capillary performance reproducibility have been studied.