Related Experiment Video
Updated: Aug 21, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Secondary prevention strategies in ischemic stroke: identification and optimal management of modifiable risk factors
Kelly D Flemming1, Robert D Brown
1Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA.
Insights
Managing modifiable ischemic stroke risk factors and using antithrombotic therapy can prevent recurrent strokes and reduce long-term harm. This review focuses on atherosclerotic factors like hypertension and hyperlipidemia.
Area of Science:
- Neurology
- Cardiology
- Public Health
Background:
- Ischemic stroke poses significant risks for morbidity, mortality, and healthcare costs.
- Patients with ischemic stroke, particularly those with carotid or lacunar disease, are also at high risk for coronary artery disease.
- Effective management of modifiable risk factors is crucial for preventing both recurrent stroke and cardiovascular events.
Purpose of the Study:
- To review known risk factors for ischemic stroke.
- To outline current treatment recommendations, emphasizing atherosclerotic risk factors.
- To discuss challenges and strategies in managing these risk factors in stroke patients.
Main Methods:
- Literature review of established and emerging risk factors for ischemic stroke.
- Analysis of current guidelines for managing atherosclerotic risk factors in stroke patients.
- Focus on recent data concerning hypertension and hyperlipidemia management.
Main Results:
- Identification and management of modifiable risk factors, alongside antithrombotic therapy, reduce stroke recurrence and long-term complications.
- Atherosclerotic risk factors are key targets for preventing both stroke and coronary artery disease in affected patients.
- Recent data highlight the importance of addressing hypertension and hyperlipidemia.
Conclusions:
- Systematic awareness and application of risk factor management by healthcare providers are essential.
- Preventing recurrent stroke and coronary artery disease requires a comprehensive approach to modifiable risk factors.
- Overcoming management challenges through strategic interventions can improve patient outcomes.
Abstract:
The identification and treatment of modifiable Ischemic stroke risk factors, in addition to appropriate antithrombotic therapy, can reduce the likelihood of first or recurrent stroke, prevent long-term morbidity and mortality after first stroke or transient Ischemic attack, and lower health care costs. Long-term morbidity and mortality in patients with ischemic stroke includes patients with coronary artery disease. Therefore, in patients with ischemic stroke (especially those with carotid artery disease and lacunar disease), the goal is to prevent not only recurrent stroke but also coronary artery disease. Neurologists and general practitioners must be aware of the specific risk factors and recommendations for patients with ischemic stroke and apply the information systematically. We review known risk factors for ischemic stroke and current recommendations for treatment, focusing primarily on atherosclerotic risk factors as they apply to patients with stroke. In particular, recent data on hypertension and hyperlipidemia are described. In addition, we discuss the challenges in managing these risk factors and the potential strategies for overcoming them.
Related Concept Videos
Atherosclerosis III: Management
Atherosclerosis IV: Nursing Management
Coronary Artery Disease IV: Preventive Measures
Ischemic Stroke l: Introduction
Acute Coronary Syndrome IV: Interprofessional Care
Angina IV: Management