Safety, efficacy, and stability indices of LASEK correction in moderate myopia and astigmatism
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Published on: September 20, 2024
Suphi Taneri1, Rachel Feit, Dimitri T Azar
1Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and the Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02114, USA.
Purpose:
To evaluate the visual outcomes and complications in low to moderate levels of myopia and astigmatism treated with laser-assisted subepithelial keratectomy (LASEK) with a focus on postoperative recovery.
Setting:
Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.
Methods:
A retrospective analysis of a case series of eyes treated with LASEK from 1996 to July 2002 with a follow-up of 2 years was performed. The LASEK technique involved creating an epithelial flap with 25 to 45 seconds of exposure to 20% alcohol, ablating the corneal surface using 3 different excimer lasers and nomogram adjustment, and repositioning the flap and applying a bandage contact lens. The main outcome measures were uncorrected visual acuity (UCVA), efficacy index, manifest refraction, best spectacle-corrected visual acuity (BSCVA), safety index, retreatment rate, and complications.
Results:
One hundred seventy-one eyes (85 right eyes and 86 left eyes) of 105 patients were studied. Preoperatively, the mean spherical equivalent was -2.99 diopters (D) +/- 1.43 (SD) (range -0.38 to -7.75 D) and the mean cylinder, -0.78 +/- 0.73 D. The UCVA ranged from 20/800 to 20/32, and the BSCVA ranged from 20/63 to 20/16; the median was 20/20. One week postoperatively, 96% of eyes had a UCVA of 20/40 or better but definitive visual recovery took more than 4 weeks in some eyes. Approximately 95% of eyes were within +/-1.0 D of emmetropia after 4 to 52 weeks; the remaining 5% did not show major deviations. At 4 to 52 weeks, only 1 eye was overcorrected by more than 1.0 D of manifest refraction. The safety index remained close to 1.0 for the follow-up after 4 weeks. The efficacy index displayed a plateau at 0.9 from 1 month to 1 year. No serious complication (including recurrent erosion syndrome) was encountered. The mean follow-up was 31 weeks, and the retreatment rate was 2.9% up to 2 years of follow-up.
Conclusions:
The long-term safety and effectiveness of LASEK for the correction of low to moderate myopia and astigmatism were demonstrated. The treatment effect stabilized after 4 weeks.
