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[Enuresis in children with sickle cell disease]

J R Mabiala Babela1, R Loumingou, A Pemba-Loufoua

  • 1Service de pédiatrie, CHU de Brazzaville, BP 32, Congo. j.mabiala.babela@caramail.com <j.mabiala.babela@caramail.com>

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|October 12, 2004
PubMed

Insights

Enuresis (bedwetting) is common in children with sickle cell disease (SCD), affecting over 50%. Higher rates of enuresis correlate with disease severity, including anemia and pain crises.

Area of Science:

  • Pediatric Hematology
  • Urology
  • Epidemiology

Background:

  • Sickle cell disease (SCD) is a genetic blood disorder with significant health implications for children.
  • Enuresis, or involuntary urination during sleep, is a common childhood condition, but its prevalence in children with SCD is not well-established.

Purpose of the Study:

  • To investigate the prevalence and characteristics of enuresis in children with sickle cell disease (SCD).
  • To identify potential risk and etiological factors associated with enuresis in this population.

Main Methods:

  • A cross-sectional study involving 987 children aged 5-20 years.
  • Two groups were compared: 456 children with sickle cell disease (hemoglobin SS) and 531 healthy children, matched for age and sex.

Main Results:

  • Enuresis prevalence was significantly higher in children with SCD (50.9%) compared to controls (16.4%).
  • Higher rates were observed in girls and persisted at age 16. Anemia and painful crises were linked to enuresis. A negative correlation was found between hemoglobin F levels and enuresis.
  • The frequency of wet nights was significantly higher in the SCD group.

Conclusions:

  • Enuresis is a frequent complication in children with sickle cell disease.
  • The intensity of enuresis is associated with the severity of the underlying SCD, suggesting a link between disease activity and bladder control.
Abstract

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