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Related Experiment Videos

Well-defined calcium initiators for lactide polymerization.

Malcolm H Chisholm1, Judith C Gallucci, Khamphee Phomphrai

  • 1Department of Chemistry, The Ohio State University, 100 West 18th Avenue, Columbus, Ohio 43210-1185, USA. chisholm@chemistry.ohio-state.edu

Inorganic Chemistry
|October 13, 2004
PubMed
Summary

New calcium amide and aryloxide complexes exhibit high activity and stereoselectivity in lactide ring-opening polymerization. These catalysts offer promising applications in biodegradable polymer synthesis.

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Area of Science:

  • Organometallic Chemistry
  • Polymer Science
  • Catalysis

Background:

  • Calcium complexes are increasingly explored as alternatives to traditional rare-earth metal catalysts in polymerization.
  • Developing efficient and stereoselective catalysts for lactide polymerization is crucial for producing biodegradable polymers like polylactic acid.
  • Monomeric calcium complexes with bulky ligands can offer unique reactivity and selectivity profiles.

Purpose of the Study:

  • To synthesize and characterize novel monomeric amide and aryloxide calcium complexes.
  • To investigate the catalytic activity and stereoselectivity of these complexes in the ring-opening polymerization of lactide.
  • To explore the structural and reactivity relationships of these calcium complexes.

Main Methods:

Related Experiment Videos

  • Synthesis of monomeric calcium complexes with bulky tris-pyrazolyl borate (Tp) or other nitrogen-based ligands (L) and amide or aryloxide (X) functionalities.
  • Characterization of the synthesized complexes using spectroscopic techniques and single-crystal X-ray diffraction.
  • Evaluation of catalytic performance in the ring-opening polymerization of lactide, including stereoselectivity studies.

    • Main Results:

    • A series of monomeric amide or aryloxide calcium complexes (LCaX) were successfully prepared and characterized.
    • The (tris-pyrazolyl borate)calcium complexes, specifically (Tp(tBu))CaX, demonstrated high activity and stereoselectivity in lactide polymerization.
    • A propylene oxide complex, (Tp(tBu))Ca(OC(6)H(3)-2,6-).(PO), was isolated and structurally characterized, showing inertness towards propylene oxide polymerization.

    Conclusions:

    • Monomeric calcium complexes with bulky ligands are effective catalysts for the stereoselective ring-opening polymerization of lactide.
    • The choice of ligand and ancillary group significantly influences the catalytic activity and selectivity.
    • These findings contribute to the development of new catalytic systems for sustainable polymer production.