Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Aromatic interactions in peptides: impact on structure and function.

Marcey L Waters1

  • 1Department of Chemistry, CB 3290, University of North Carolina, Chapel Hill, NC 27599, USA.

Biopolymers
|October 13, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of an Imprint-and-Report Sensor Array for Detection and Differentiation of Perfluorooctanoic Acid Precursors.

Journal of the American Chemical Society·2026
Same author

Influence of the Electrostatic Tuning of Alkyl and Benzyl Groups on Cation-π Interactions in Histone Reader Proteins and β-Hairpin Peptides.

Biochemistry·2026
Same author

Evaluation of Cooperative Binding of Histone Post-Translational Modifications and the Surrounding Sequence by Trimethyllysine Reader Proteins.

Biochemistry·2025
Same author

The role of multivalency in the association of the eight twenty-one protein 2 (ETO2) with the nucleosome remodeling and deacetylase (NuRD) complex.

Nucleic acids research·2025
Same author

Negative Cooperativity in the UHRF1 TTD-PHD Dual Domain Masks the Contributions of Cation-π Interactions between Trimethyllysine and the TTD Aromatic Cage.

Chemistry (Weinheim an der Bergstrasse, Germany)·2025
Same author

Anion-Facilitated Hydrogen-Deuterium Exchange as a Tool to Probe Weak Anion-Protein Interactions Responsible for Hofmeister Effects.

The journal of physical chemistry. B·2025
Same journal

Synthesis, Characterization, and Antidiabetic Evaluation of Sequence-Modified Liraglutide Analogs in a Drosophila melanogaster Model.

Biopolymers·2026
Same journal

Fabrication of an Antibacterial Alginate/Chitosan Hydrogel Dressing Loaded With CuO Nanoparticles for Wound Dressing Applications.

Biopolymers·2026
Same journal

Effect of Chitosan-Alginate Polyelectrolyte Complex Formation and Multilayer Polymer Configuration on the Characteristics of 3D-Printed Metronidazole-Loaded Periodontal Films.

Biopolymers·2026
Same journal

Phenolic Grafting of Oxidized Cellulose Nanofibers Using Ferulic Acid: Structural and Antioxidant Analysis Toward Bioactive Nanomaterials.

Biopolymers·2026
Same journal

Detection of a Target Nucleic Acid by Ligation-Assisted Fluorescence Enhancement of a Peptide Nucleic Acid (PNA) Twin Probe via Disulfide Binding.

Biopolymers·2026
Same journal

Influence of the Adsorption Time on the Growth of Bovine Serum Albumin-Chondroitin Sulfate Multilayer Films: A Surface Plasmon Resonance Spectroscopy Study.

Biopolymers·2026
See all related articles

Aromatic interactions like pi-pi and cation-pi are key in protein structure. Studies on structured peptides reveal their crucial role in protein function and stability.

Area of Science:

  • Biochemistry
  • Structural Biology
  • Computational Chemistry

Background:

  • Aromatic interactions (pi-pi, cation-pi, aryl-sulfur, carbohydrate-pi) are frequently observed in protein structures.
  • Previous analyses of protein structures suggest the importance of aromatic interactions.
  • The precise magnitude and functional significance of these interactions remain incompletely defined.

Purpose of the Study:

  • To review recent advances in understanding aromatic interactions within structured peptides.
  • To explore the role of aromatic interactions in protein structure and function.
  • To complement existing protein structure analysis with insights from peptide studies.

Main Methods:

  • Review of recent scientific literature on aromatic interactions in peptides.

Related Experiment Videos

  • Analysis of data from structured peptide investigations.
  • Comparison of findings from peptide studies with broader protein structure analyses.

    • Main Results:

    • Structured peptide studies provide valuable insights into the significance of aromatic interactions.
    • These interactions are confirmed as important contributors to both protein structure and biological function.
    • Recent research has elucidated specific roles and mechanisms of various aromatic interactions.

    Conclusions:

    • Aromatic interactions are fundamental to protein architecture and function.
    • Investigating structured peptides offers a powerful approach to defining the roles of these interactions.
    • Further research continues to uncover the detailed mechanisms and importance of aromatic interactions in biological systems.