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Updated: Aug 21, 2026
Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Psoriasis remission after laparoscopic Roux-en-Y gastric bypass for morbid obesity
Guillermo Higa-Sansone1, Samuel Szomstein, Flavia Soto
1The Bariatric Institute, Cleveland Clinic Florida, Weston, FL 33331, USA.
Background:
Psoriasis is a chronic skin disease characterized by epithelial hyperplasia and an accelerated rate of epithelial turnover affecting approximately 1-3% of the population. Exogenous and endogenous factors including morbid obesity can increase the morbidity of psoriasis.
Case Report:
A 55-year-old male, who weighed 131 kg with BMI 41 kg/m2, underwent laparoscopic Roux-en-Y gastric bypass (LRYGBP). He had a 15-year duration of severe psoriasis and was being medically treated. At 12 months after LRYGBP, he had lost 39 kg (68% EWL), and had complete resolution of the psoriasis and had discontinued all preoperative medications related to the disease. At 2 years after LRYGBP, psoriasis has not recurred.
Conclusion:
Weight loss after LRYGBP should be considered as a strategy in the treatment of severe psoriasis in morbidly obese patients.
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