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Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Can chest X-ray predict pneumonia severity?
Olga Grafakou1, Maria Moustaki, Maria Tsolia
1Second Department of Pediatrics, University of Athens, P. and A. Kyriakou Children's Hospital, Athens, Greece. grafakou@hol.gr
Insights
Chest X-ray findings like consolidation size and location predict childhood pneumonia severity. Left-sided pneumonia, particularly with pleural effusion, indicates a more severe disease course in children.
Area of Science:
- Pediatrics
- Radiology
- Infectious Diseases
Background:
- Predicting childhood pneumonia severity is crucial for effective management.
- Chest radiographic findings are not fully explored as severity predictors in developed nations.
Purpose of the Study:
- To evaluate chest radiographic findings as predictors of childhood pneumonia severity.
- To identify specific radiological markers associated with prolonged illness and hospitalization.
Main Methods:
- Retrospective analysis of 167 children over 12 months old hospitalized with unilateral lobar or segmental pneumonia.
- Severity indicators included duration of fever and hospitalization.
- Statistical analysis including univariate and multiple logistic regression.
Main Results:
- Consolidation size and left-sided location were independently associated with pneumonia severity.
- Left-sided pneumonia showed longer fever duration, longer hospitalization, and higher pleural effusion prevalence.
- Pleural effusion was significantly more likely in left-sided pneumonia (OR 2.65, P=0.031).
Conclusions:
- Chest X-ray findings, specifically consolidation size and location, can predict pneumonia severity in children.
- Left-sided pneumonia courses are generally more severe, potentially due to increased pleurisy risk.
Abstract:
Predictors of the severity of pneumonia have not been thoroughly evaluated among children in developed countries. We investigate whether chest radiographic findings could be used as predictors of severity of childhood pneumonia. The study included 167 children, aged more than 12 months, hospitalized in our department during a 4-year period with unilateral lobar or segmental pneumonia. The durations of fever and of hospitalization were considered indicators of severity of the disease. The size of the consolidation and its location in the left hemithorax were independently associated with severity of the disease. Univariate analysis showed that the mean duration of fever and of hospitalization as well as the prevalence of pleural effusion was significantly higher among children with left-sided pneumonia. A multiple logistic regression analysis revealed that only the presence of pleural effusion was significantly more likely in left-sided pneumonia (odds ratio, 2.65; 95% confidence interval, 1.09-6.47; P = 0.031). We conclude that the size of consolidation and the side of its location can be used as predictors of severity of pneumonia, with left-sided pneumonia running a more severe course, possibly due to increased risk for the development of pleurisy.
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