Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Infectious complications after hepatic resection.

Robert A Garwood1, Robert G Sawyer, Lee Thompson

  • 1Department of Surgery, University of Virginia, Charlottesville, Virginia 22908-0709, USA.

The American Surgeon
|October 16, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Antibiotic use in emergency general surgery: What you need to know.

The journal of trauma and acute care surgery·2026
Same author

Case Report: Nonoperative management of traumatic dual-vessel hepatic infarction.

Frontiers in surgery·2026
Same author

Highlights from the 38th Annual Meeting of the Japanese Society of Surgical Infection.

Surgical infections·2026
Same author

Publisher Correction: Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2026.

Intensive care medicine·2026
Same author

Hand Deserve Better: global clinical consensus recommendations on surgical gloving practice.

The Journal of hospital infection·2026
Same author

Executive Summary: Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026.

Critical care medicine·2026

Surgical infections after hepatic resection (HR) significantly impact mortality. Key risk factors include advanced age, comorbidities, extent of resection, ventilator dependence, and delayed antibiotic treatment, especially with resistant bacteria.

Area of Science:

  • Hepatobiliary Surgery
  • Surgical Infections
  • Postoperative Mortality

Background:

  • Hepatic resection (HR) has seen reduced morbidity and mortality due to surgical advances.
  • However, surgical site infections (SSIs) remain a significant cause of postoperative complications and death following HR.
  • Understanding infection characteristics is crucial for improving patient outcomes.

Purpose of the Study:

  • To analyze the characteristics of surgical infections after HR.
  • To identify factors associated with increased postoperative mortality after HR.
  • To inform strategies for reducing infection-related deaths.

Main Methods:

  • Retrospective analysis of 207 HR procedures over 7 years.
  • Comparison with a prospective surgical infection database.

Related Experiment Videos

  • Identification of factors contributing to infectious complications and mortality.

    • Main Results:

    • Overall mortality was 5.8%; 3.3% of patients experienced 18 infections.
    • Infections commonly involved the peritoneum, blood, or wound; 2/3 of infection-related deaths had lung or line infections.
    • Risk factors for mortality included ventilator dependence, resection of ≥4 segments, advanced age, multiple comorbidities, and delayed antibiotic therapy (mean 13.3 days).
    • Methicillin-resistant Staphylococcus species were implicated in all infection-related deaths.

    Conclusions:

    • Infectious mortality after HR remains a significant clinical concern.
    • Advanced age, multiple comorbidities, extent of resection, ventilator dependence, and delayed antibiotic treatment are key risk factors for mortality.
    • While gram-negative infections are common, gram-positive infections (especially with antibiotic-resistant strains) are associated with higher mortality.