Related Experiment Video
Updated: Jul 12, 2026

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
Published on: November 19, 2012
[Study of synaptic plasticity of hippocampal CA3 area as a result of tetanization of perforant path]
Abstract:
Evoked responses in CA3 area to the mossy fibers stimulation were studied after low and high frequency tetanizations of the perforant path. Stimulations of perforant path with 10 and 100 Hz frequencies inducted depression testing through the same path. Subthreshold for potentiation of the mossy fibers inputs to the CA3 tetanization of the perforant path with 10 Hz frequency transformed to threshold one after previous tetanization of the perforant path with 100 Hz frequency. Tetanization of the mossy inputs to the CA3 with 10 Hz frequency leaded to potentiation whereas tetanization with frequency 100 Hz depressed the same inputs. High frequency tetanizations (100 Hz) of the perforant path with theta-rithm frequency stimulation basically depressed of the CA3 evoked responces to the mossy fiber stimulation.
More Related Videos
09:39Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation
Published on: June 26, 2013
14:27Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording
Published on: August 11, 2019
Related Concept Videos
Long-term Potentiation
Long-term Depression
Long-term Potentiation
Hebbian LTP
LTP can occur when presynaptic neurons...
Long-term Depression
Calcium Ion Concentration Mechanism
If over time, all...