Related Experiment Video
Updated: Aug 21, 2026

Quantification of Fungal Colonization, Sporogenesis, and Production of Mycotoxins Using Kernel Bioassays
Published on: April 23, 2012
Synthesis and fungicidal activity of ethaboxam against Oomycetes
Dal-Soo Kim1, Sam-Jae Chun, Jae-Jin Jeon
1LG Life Sciences Ltd, R&D Park, 104-1, Moonjidong, Yuseonggu, Daejeon 305-380, Korea. dalskim@lgls.co.kr
Abstract:
This study describes the chemical synthesis and intrinsic fungicidal activity of ethaboxam [(RS)-N-(alpha-cyano-2-thenyl)-4-ethyl-2-(ethylamino)-1,3-thiazole-5-carboxamide], a new Oomycetes fungicide. In in vitro tests, ethaboxam showed inhibitory activity against isolates of Phytophthora and some Pythium spp, with MIC values ranging from 0.1 to 0.5 mg litre(-1) for nine isolates of Phytophthora infestans (Montagne) de Bary and from 1.0 to 5.0 mg litre(-1) for eight isolates of Phytophthora capsici Leonian. In tests to determine time and concentration for complete inactivation of each pathogen (five isolates of P infestans and five isolates of P capsici), ethaboxam inactivated all isolates of P infestans within 48h at 10 mg litre(-1) and those of P capsici within 96 h at 10 mg litre(-1). Ethaboxam effectively suppressed development of tomato late blight caused by P infestans and pepper Phytophthora blight caused by P capsici in the studies conducted to determine its preventive, curative, persistent and systemic activity. These results show that ethaboxam has desirable fungicidal characteristics as an Oomycetes fungicide.
Related Concept Videos
Antifungal Agents
Fungal Group Zygomycota
Overview of Fungi
Anthelminthic Agents
Fungal Phylum Basidiomycota
Fungal Phylum Ascomycota
