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Burning mouth syndrome: the efficacy of lipoic acid on subgroups
Objective:
We have examined the effect of alpha-lipoic acid (ALA, tioctic acid; Tiobec), a free radical scavenger, on the discomfort of burning mouth syndrome (BMS) in patients who had used tranquillizers previously, compared with those who had not.
Methods:
In this study we gave lipoic acid for 2 months to two groups of 20 BMS patients, one of which had previously been treated with tranquillizers.
Results:
The results showed greater effectiveness of lipoic acid in BMS patients who had not previously used tranquillizers.
Conclusions:
The patients with BMS who had previously been treated with tranquillizers responded poorly to therapy with lipoic acid compared with those who had not received previous psychotropic therapy.
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