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Updated: Aug 12, 2026

Radiation Treatment of Organotypic Cultures from Submandibular and Parotid Salivary Glands Models Key In Vivo Characteristics
Published on: May 17, 2019
Aplasia of submandibular salivary glands associated with ectodermal dysplasia
Parmjit Singh1, Saman Warnakulasuriya
1Department of Oral Medicine, Guy's, King's and St Thomas' Dental Institute, Denmark Hill Campus, London, UK.
Abstract:
We describe a 28-year-old white Caucasian man displaying many of the physical signs of ectodermal dysplasia (ED). An unusual finding was his presentation with xerostomia. Salivary gland imaging techniques revealed aplasia of both submandibular salivary glands and relatively small parotids. The case highlights that hypoplasia and aplasia of exocrine glands could be rare features of ED. In the management of ED, early detection of xerostomia is important to limit any potential damage to the already hypodontic dentition.
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