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The diagnostic value of skin prick testing in children with food allergy
David J Hill1, Ralf G Heine, Clifford S Hosking
1Department of Allergy, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia. allergy.clinic@rch.org.au
Abstract:
The diagnostic accuracy of the skin prick test (SPT) in food allergy is controversial. We have developed diagnostic cut-off levels for SPT in children with allergy to cow milk, egg and peanut. Based on 555 open food challenges in 467 children (median age 3.0 yr) we defined food-specific SPT weal diameters that were '100% diagnostic' for allergy to cow milk (>or=8 mm), egg (>or=7 mm) and peanut (>or=8 mm). In children < 2 yr of age, the corresponding weal diameters were >or=6 mm, >or=5 mm and >or=4 mm, respectively. These SPT cut-off levels were prospectively validated in 90 consecutive children
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