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Development of a nonmechanical enucleation method using x-ray irradiation in somatic cell nuclear transfer

Tae M Kim1, Woo S Hwang, Ji H Shin

  • 1School of Agricultural Biotechnology, Seoul National University, Seoul, Korea.

Fertility and Sterility
|October 16, 2004
PubMed

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Nuclear reprogramming is the process of switching gene expression of one cell type to that of another cell type, usually from a differentiated cell state to an undifferentiated cell state. Differentiation occurs during processes such as development and morphogenesis, tissue regeneration, and malignancy. Cells can also be artificially induced to reprogram their gene expression by techniques such as nuclear transfer, induced pluripotency, and cell fusion. Such techniques have many applications in...