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Updated: Aug 21, 2026
Rapid Detection of Fecal Antigen of Helicobacter pylori Infection Based on Double Antibody Sandwich Detection Technology
Published on: May 23, 2025
Helicobacter pylori seroprevalence in patients with lung cancer
Nikiphoros Philippou1, Panagiotis Koursarakos, Evgenia Anastasakou
19th Department of Pulmonary Medicine, SOTIRIA Chest Diseases Hospital, 152 Mesogion Street, PO Box 11527, Athens, Greece. roumar26@yahoo.com
Aim:
To assess Helicobacter pylori (H pylori) seroprevalence in a cohort of Greek patients with lung cancer.
Methods:
Seventy-two lung cancer patients (55 males and 17 females, aged 58.2+/-11.7 years) and 68, age and gender-matched, control subjects were enrolled. All subjects underwent an enzyme-linked immunosorbent assay IgG serologic test for H pylori diagnosis.
Results:
A correlation between age and H pylori IgG level was detected for both lung cancer patients (r = 0.42, P = 0.004) and controls (r = 0.44, P = 0.004). Seropositivity for H pylori did not differ significantly between patients with lung cancer and controls (61.1% vs 55.9%, P>0.05). Concerning the mean serum concentration of IgG antibodies against H pylori, no significant difference between the two groups was detected (32.6+/-19.1 vs 27.4+/-18.3 U/mL, P>0.05).
Conclusion:
No significant association between H pylori infection and lung cancer was found.
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