[Do enzyme determinations have any prognostic value in neurotraumatology?]

In 34 cases of skull traumas and in 14 cases of acute cerebral accidents, CK, GOT, GPT, LDH and its isoenzymes were assessed in the patient's serum and CSF. Results show that the increase of the enzymatic level in the CSF seems due to cerebral tissue damage for the main part, when in the serum the increase is influenced by combined traumas. The CSF dosages allow to define a threshold of severeness, unlike serum dosages without any pronostic value.