Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Medical genetics in developing countries.

Arnold Christianson1, Bernadette Modell

  • 1Division of Human Genetics, National Health Laboratory Service and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2000, South Africa. arnold.christianson@nhls.ac.za

Annual Review of Genomics and Human Genetics
|October 16, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Modelled epidemiological data for selected congenital disorders in South Africa.

Journal of community genetics·2021
Same author

The Prevention of Thalassemia Revisited: A Historical and Ethical Perspective by the Thalassemia International Federation.

Hemoglobin·2021
Same author

Haemoglobin disorders-a point of entry for community genetics services in India?

Journal of community genetics·2019
Same author

Congenital disorders: epidemiological methods for answering calls for action.

Journal of community genetics·2018
Same author

Estimating the birth prevalence and pregnancy outcomes of congenital malformations worldwide.

Journal of community genetics·2018
Same author

Historical overview of development in methods to estimate burden of disease due to congenital disorders.

Journal of community genetics·2018
Same journal

Common Principles Underlie Mitochondrial DNA Heteroplasmy Dynamics in the Germline and Soma.

Annual review of genomics and human genetics·2026
Same journal

Human Sex Chromosome Biology in the Genomic Era.

Annual review of genomics and human genetics·2026
Same journal

Beyond TADs and Compartments: Mesoscale Chromatin Folding and Its Dynamics in Transcriptional Regulation.

Annual review of genomics and human genetics·2026
Same journal

Experimental and Computational Approaches to Identify Noncoding Pathogenic Variation in Rare Disease.

Annual review of genomics and human genetics·2026
Same journal

How Studying Rare Disease Leads to Mechanistic Insights and Therapeutic Development: Lessons from Nonmammalian Models.

Annual review of genomics and human genetics·2026
Same journal

Synthetic Regulatory Genomics.

Annual review of genomics and human genetics·2026
See all related articles

Developing nations face a growing burden of congenital disorders. This study introduces a new, pragmatic approach to care and prevention, leveraging World Health Organization initiatives for these underserved regions.

Area of Science:

  • Genetics
  • Public Health
  • Epidemiology

Background:

  • Since the discovery of DNA structure in 1953, advancements in congenital disorder control have primarily benefited industrialized nations.
  • Developing countries are experiencing an epidemiological transition, increasing the public health significance of congenital disorders.
  • These lower-resource nations face a substantial burden from congenital disorders and require enhanced medical genetic services.

Purpose of the Study:

  • To present a novel, pragmatic strategy for managing and preventing congenital disorders in developing countries.
  • To address the growing public health challenge posed by congenital disorders in resource-limited settings.
  • To build upon existing World Health Organization (WHO) frameworks for genetic services.

Main Methods:

Related Experiment Videos

  • The study outlines a pragmatic approach, likely involving policy recommendations and service delivery models.
  • It emphasizes the need for developing medical genetic services tailored to the context of developing nations.
  • The approach is informed by the World Health Organization's (WHO) public health initiatives.

Main Results:

  • The proposed approach aims to improve the care and prevention of congenital disorders in developing countries.
  • It seeks to mitigate the high burden of these conditions in resource-limited settings.
  • The strategy is designed to be adaptable and implementable within the existing healthcare infrastructure.

Conclusions:

  • A pragmatic, WHO-supported approach is crucial for addressing the rising burden of congenital disorders in developing nations.
  • Developing medical genetic services is essential for effective prevention and care.
  • This strategy offers a pathway to improve health outcomes for congenital disorders in underserved populations.