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Detecting and managing patients with type 2 diabetic kidney disease: proteinuria and cardiovascular disease
William E Mitch1, Shahnaz Shahinfar, Tania Z Dickson
1University of Texas Medical Branch, Galveston, Texas, USA. wmitch@utmb.edu
Background:
The increasing prevalence of type 2 diabetes (T2DM) places more patients at risk for developing chronic kidney disease (CKD) or cardiovascular (CV) events. Effective therapy for CKD or CV disease (CVD) requires a method of identifying affected patients and monitoring the effectiveness of therapy.
Methods:
We tested the predictive value of proteinuria for identifying patients at risk for progressive CDK and CVD, and monitoring treatment was determined using RENAAL study results.
Results:
Baseline proteinuria identified patients at risk for progressive CKD and CVD. Suppression of proteinuria was associated with decreased likelihood of CKD or CVD.
Conclusion:
Proteinuria identifies the risk of CKD and CVD, and can be used to monitor the effectiveness of therapy.
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