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Updated: Aug 21, 2026
Studying the Effects of Inhaled Environmental Pollutants on Olfactory Function in Mice
Published on: September 13, 2024
Olfactory loss in poly (acrylonitrile-butadiene-styrene) plastic injection-moulding workers
Shu-Fang Cheng1, Mei-Lien Chen, Po-Chen Hung
1Institute of Public Health, National Yang-Ming University, Taipei, Taiwan. chengsf@mail.iosh.gov.tw
Background:
Plastics manufacturing factories are the fifth largest category of factories in industrial estates in Taiwan. It is known that complex airborne compounds and pungent odours are emitted during plastic injection-moulding processes. Workers exposed to acrylonitrile-butadiene-styrene (ABS) thermal decomposition products (TDP) may have olfactory loss.
Aims:
This study examined olfactory loss in injection-moulding workers exposed to ABS TDP.
Methods:
The method recommended by the Connecticut Chemosensory Clinical Research Center (CCCRC) was used to test the olfactory function of subjects, including 1-butanol threshold and odour identification, both pre- and post-work. The study sample included 52 ABS plastic injection-moulding workers (exposed group), as well as 72 workers from other departments (reference group).
Results:
The results revealed that the exposed group had lower olfactory function after work than the reference group. The decrease in olfactory function after 1 workday was statistically significant. The prevalence of abnormal olfactory function post-work in the exposed group was higher than in the reference group.
Conclusions:
The findings of this study implied the ABS plastic injection-moulding process may worsen olfactory function among workers. Notably, this effect decreased olfactory threshold scores, not odour identification scores.
