Vascular access results from the Dialysis Outcomes and Practice Patterns Study (DOPPS): performance against Kidney

Hugh C Rayner1, Anatole Besarab, Wendy W Brown

  • 1Birmingham Heartlands Hospital, United Kingdom.

Insights

Native arteriovenous (AV) fistulae are recommended for hemodialysis vascular access. However, AV fistula use varies globally, with the US lagging behind Europe and Japan, and catheter use is concerningly increasing.

Area of Science:

  • Nephrology
  • Vascular Surgery
  • Public Health

Background:

  • Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines advocate for native arteriovenous (AV) fistulae over grafts or catheters for hemodialysis.
  • Guidelines recommend a maturation period of at least one month before AV fistula cannulation.

Purpose of the Study:

  • To examine international vascular access practice patterns and guideline adherence using the Dialysis Outcomes and Practice Patterns Study (DOPPS).
  • To investigate the association between vascular access choices and mortality risk in hemodialysis patients.

Main Methods:

  • Analysis of data from the Dialysis Outcomes and Practice Patterns Study (DOPPS), an international research initiative.
  • Comparison of vascular access modalities (AV fistula, AV graft, tunneled catheter) and their associated outcomes across different countries.

Main Results:

  • Significant international variation exists in AV fistula utilization; Europe and Japan predominantly use fistulae, while the US uses more grafts.
  • Patients receiving pre-dialysis care for over 30 days show higher rates of AV fistula initiation.
  • Tunneled catheters are associated with increased mortality and subsequent fistula failure, with their use increasing globally.
  • US dialysis facilities show longer fistula maturation times but worse fistula survival compared to European centers.

Conclusions:

  • DOPPS data indicate disparities in practice patterns and guideline adherence across countries.
  • Continued monitoring by DOPPS is essential to assess if improved guideline application can reduce access complications and enhance hemodialysis patient longevity.
Abstract

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