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Related Experiment Videos

Dynamic changes of nasal resistance.

M Hasegawa, E B Kern, P C O'Brien

    The Annals of Otology, Rhinology, and Laryngology
    |January 1, 1979
    PubMed
    Summary

    Normal nasal resistance fluctuates physiologically. A change exceeding 53% in nasal resistance over 15 minutes in healthy individuals suggests a significant deviation beyond normal variability.

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    Area of Science:

    • Otolaryngology
    • Physiology

    Background:

    • Nasal resistance is a key metric in respiratory function.
    • Understanding normal physiological ranges is crucial for accurate diagnosis.

    Purpose of the Study:

    • To establish a baseline for the dynamic range of nasal resistance in healthy subjects.
    • To differentiate physiological variability from pathological changes in nasal resistance.

    Main Methods:

    • Posterior rhinomanometry was used to evaluate 50 human subjects.
    • Data analysis focused on average resistance, average change, and maximal expected change over 15-minute intervals.

    Main Results:

    • Over 1,272 observations were analyzed to justify the concept of percent change in nasal resistance.
    • Physiological change in nasal resistance in normal individuals over 15 minutes should be less than 53%.

    Conclusions:

    • A nasal resistance change greater than 53% indicates a significant deviation not attributable to normal physiological variability.
    • This finding provides a benchmark for assessing nasal responses to various challenges.

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