Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Circadian rhythms in microorganisms: new complexities.

Patricia L Lakin-Thomas1, Stuart Brody

  • 1Department of Biology, York University, Toronto, ON M3J 1P3, Canada. plakin@yorku.ca

Annual Review of Microbiology
|October 19, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Shared Components of the FRQ-Less Oscillator and TOR Pathway Maintain Rhythmicity in <i>Neurospora</i>.

Journal of biological rhythms·2021
Same author

Rationalization is a suboptimal defense mechanism associated with clinical and forensic problems.

The Behavioral and brain sciences·2020
Same author

A Comparison of the <i>Neurospora</i> and <i>Drosophila</i> Clocks.

Journal of biological rhythms·2019
Same author

Circadian Rhythms in Fungi: Structure/Function/Evolution of Some Clock Components.

Journal of biological rhythms·2019
Same author

Specifically Penile-Vaginal Intercourse Frequency Is Associated With Better Relationship Satisfaction: A Commentary on Hicks, McNulty, Meltzer, and Olson (2016).

Psychological science·2017
Same author

An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female anorectal dysfunction.

International urogynecology journal·2016
Same journal

Circadian Control of Host-Microbiome Symbioses.

Annual review of microbiology·2026
Same journal

Host-Pathogen Interactions in Malaria: Invasion, Neutralization, and Evasion.

Annual review of microbiology·2026
Same journal

From an Interest in Molecules to a Fascination with Microbes.

Annual review of microbiology·2026
Same journal

Bacterial Physiology in the Context of Algal Partners.

Annual review of microbiology·2026
Same journal

Introduction.

Annual review of microbiology·2025
Same journal

Decoding Microbial Community Assembly: Insights on Vectors of Infectious Diseases.

Annual review of microbiology·2025
See all related articles

Circadian rhythms in Neurospora, Gonyaulax, and Synechococcus are more complex than previously thought. New research reveals multiple inputs, oscillators, outputs, and feedback loops in these daily biological timing systems.

Area of Science:

  • Chronobiology
  • Molecular Biology
  • Systems Biology

Background:

  • Circadian rhythms govern daily biological processes.
  • Previous models depicted a simple input-oscillator-output pathway.
  • Understanding these rhythms is crucial across diverse organisms.

Purpose of the Study:

  • To review recent advances in circadian rhythm research.
  • To describe new complexities in circadian systems.
  • To present experimental evidence for novel oscillator mechanisms.

Main Methods:

  • Literature review of circadian systems in Neurospora, Gonyaulax, and Synechococcus.
  • Analysis of posttranscriptional regulation within the frq/white-collar oscillator (FWC).
  • Presentation of experimental data supporting frq-less oscillators (FLO).

Related Experiment Videos

Main Results:

  • Circadian systems exhibit multiple input, oscillator, and output pathways.
  • Feedback loops exist from oscillator to input and output to oscillator.
  • Posttranscriptional modifications, including protein phosphorylation and degradation, are key to FWC function.
  • Evidence for frq-less oscillators (FLO) downstream of the FWC was found.

Conclusions:

  • Circadian systems are highly complex and interconnected.
  • Posttranscriptional regulation plays a significant role in circadian timing.
  • New models are needed to encompass the expanded understanding of circadian complexity.