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Published on: June 5, 2026
The health of young people in a global context
Robert W Blum1, Kristin Nelson-Mmari
1Center for Adolescent Health and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA. blumx001@umn.edu
Insights
Global youth mortality trends show a shift from infectious diseases to social causes like unintentional injuries and violence. Understanding these factors is key to improving adolescent health worldwide.
Area of Science:
- Global Health
- Adolescent Health
- Public Health
Background:
- Adolescent morbidity and mortality patterns have historically been influenced by infectious diseases.
- Recent shifts indicate a growing impact of social and behavioral factors on young people's health outcomes.
Purpose of the Study:
- To investigate the primary causes and contributing factors of morbidity and mortality in young people globally.
- To analyze trends and shifts in adolescent health challenges worldwide.
Main Methods:
- Comprehensive literature review of global health databases (e.g., WHO Global Burden of Disease, Medline) and expert consultations.
- Inclusion of studies post-1985, with sample sizes >= 100, focusing on ages 10-24.
- Examination of diverse health issues including injuries, HIV/AIDS, suicide, homicide, war, maternal mortality, and substance abuse.
Main Results:
- A significant transition from infectious etiologies to social factors driving adolescent morbidity and mortality.
- Unintentional injury identified as the leading cause of death for young people globally.
- Homicide, war, and interpersonal violence are major contributors to youth mortality, following closely behind injuries.
Conclusions:
- Demographic shifts, including changes in population, migration, marriage age, and education, significantly impact adolescent health.
- Understanding the evolving determinants of adolescent morbidity and mortality is crucial for developing effective global health interventions.
- Identifying key influences allows for targeted strategies to enhance the well-being of youth worldwide.
Purpose:
To examine the chief causes and influences of morbidity and mortality among young people throughout the world.
Methods:
A comprehensive literature search was conducted that included WHO's Global Burden of Disease, UNFPA's State of the Worlds' Population, Medline, Popline, Sociological Abstracts, as well as data collected from UNICEF, UNAIDS, Population Reference Bureau, and the United Nations Headquarters. Experts in the fields of substance use, suicide, and infectious diseases were also contacted for unpublished and published sources. Studies were restricted to those completed after 1985, had a sample size of at least 100, focused primarily on the age group of 10-24 years, and examined trends related to unintentional injuries, HIV/AIDS, suicide, homicide, war, maternal mortality, pregnancy, abortion, sexually transmitted diseases, substance abuse, and infectious diseases.
Results:
Trends in adolescent morbidity and mortality have shifted over the past decade from predominately infectious to social etiologies. Currently, unintentional injury is the leading killer of young people in nearly every region of the world, with homicide, war, and interpersonal violence following closely behind.
Conclusions:
The changes in population, migration, age of marriage, and education have had profound impact on the mortality and morbidity among adolescents. As we come to learn about the factors that influence adolescent morbidity and mortality, we begin to have a better understanding of how to improve the health of youth throughout the world.
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