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Re-structuring the host cell: up close with Salmonella's molecular machinery
1Laboratory of Structural Microbiology, Rockefeller University, New York, NY 10021, USA. stebbins@rockefeller.edu
Abstract:
A common theme in bacterial disease is the manipulation of the eukaryotic cytoskeleton by pathogenic factors. Understanding how virulence factors operate to achieve these alterations is a growing and important research effort. This review focuses on several virulence factors from the pathogen Salmonella, and considers the contributions of structural biology to our appreciation of bacterial modulation of cytoskeletal dynamics.
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