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[Intratympanic gentamicin in patients with Ménière's disease: analysis of our protocol]
E Martín Sanz1, N Pérez Fernández
1Servicio Otorrinolaringología, Hospital Casa de Salud, Valencia. emartin@clinicabarona.com
Objective:
The aim of this paper is to analyze the peculiarities of a protocol for treatment with intratympanic gentamicin in patients with Ménière's disease.
Material And Methods:
71 patients with unilateral disabling Ménière's disease were followed for a period longer than two years after concluding the treatment. AAO-HNS criteria for reporting treatment results was followed. Gentamicin was applied weekly until of symptoms or signs of vestibular hypofunction were noticed.
Results:
Control of vertigo was obtained in 83% of the patients while in 24% a second course was needed beacuse of vertigo recurrence. 66% of the patients developed a typical syndrome of unilateral vestibular hypofunction in the ear treated.
Conclusions:
Ending weekly injections of gentamicin for the treatment of patients with Ménière's disease when signs of vestibular hypofunction appear warrants a control of vertigo similar to that obtained in other series.
