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Recurrent vulvar carcinoma in pregnancy
Dele Ogunleye1, Sharyn N Lewin, Phyllis Huettner
1Department of Obstetrics and Gynecology, Good Samaritan Hospital, Cincinnati, OH, USA.
Gynecologic Oncology
|October 20, 2004
Summary
Recurrent vulvar squamous cell carcinoma during pregnancy is rare. This case highlights the need for vigilant monitoring, as recurrence can manifest swiftly during gestation.
Area of Science:
- Gynecologic Oncology
- Obstetrics
- Dermatopathology
Background:
- Vulvar carcinoma is uncommon in premenopausal women.
- Pregnancy-associated vulvar carcinoma is exceedingly rare.
- No prior reports exist of recurrent vulvar carcinoma during the same pregnancy.
Observation:
- A 36-year-old pregnant woman presented with vulvar pain and a mass.
- Biopsy confirmed invasive squamous cell carcinoma.
- Following surgery at 23 weeks gestation, recurrence (VIN III with invasive foci) was detected 11 weeks later.
Findings:
- The patient underwent modified radical vulvectomy and lymph node dissection.
- Recurrence was diagnosed and treated with local excision postpartum.
- This represents the first reported case of recurrent vulvar squamous cell carcinoma during pregnancy.
Implications:
- Pregnancy necessitates careful surveillance for vulvar squamous cell carcinoma.
- Rapid recurrence is possible even during gestation.
- Timely diagnosis and management are crucial for maternal outcomes.